Skin aging doesn’t begin at the surface. Over time, skin’s natural ability to renew itself gradually slows in deeper layers, where the earliest visible signs of aging take shape. This decline can lead to dullness, uneven tone, fine lines, and wrinkles — making skin appear less vibrant and smooth. Phyto Nature E² is Dermalogica’s next-generation leave-on exfoliant, created to visibly reverse these signs by supporting skin’s natural renewal and regeneration. By combining advanced regenerative technology with gentle daily exfoliation, it helps restore a smoother, brighter, and more youthful-looking complexion.

At the core of Phyto Nature E² is a powerful fusion of plant-based exosomes and Pumpkin Enzyme. The formula gently exfoliates to refine texture and boost radiance, while exosome technology works across multiple layers of the skin’s surface to visibly diminish fine lines and wrinkles. The result is skin that looks revitalized, renewed, and up to 6 years younger.
Building on Dermalogica’s leadership in regenerative skin care, Phyto Nature E² brings professional-level innovation into a daily at-home ritual. Following the introduction of Exo Booster — the first bacterial exosome system developed for post-procedure recovery — this new formula features plant-based exosomes designed to support everyday skin renewal. A botanical brightening blend of phyto glycogen and prickly pear helps smooth and illuminate the complexion, while bio-fermented acetyl glucosamine delivers hydration and antioxidant protection for healthier-looking skin.
Silky and leave-on, Phyto Nature E² feels light yet nourishing as it gently resurfaces and rejuvenates skin without irritation. Apply to clean skin twice daily, allow to absorb, then follow with the rest of your skin care routine. With continued use, skin appears smoother, brighter, and more refined — revealing a renewed glow powered by advanced regenerative science.

Phyto Nature E², 100ml | $229
